D-AB-10152L
Vcam1 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- D-AB-10152L
- Zusätzliche Namen:
- CD106,V-CAM 1,VCAM-1,Vascular cell adhesion protein 1,Vcam-1,Vcam1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Rat Vcam1 protein expressed by Mammalian
- Uniprot:
- P29534
- Synonyme:
- V-CAM 1;vascular cell adhesion protein 1;vascular cell adhesion protein 1-like;VCAM-1;VCAM1B
- Weitere Details:
- Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.
- Versandbedingungen:
- Blue Ice