AN302095L
Recombinant Phospho-IK KappaBA Alpha (Ser36) Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302095L
- Zusätzliche Namen:
- EDAID,MAD,IKBA,MAD-3,NFKBI,IKB alpha,NFKBIA,EDAID2,I kappa B alpha,IkappaBalpha,I-kappa-B-alpha,IKBalpha,IkB-alpha,MAD 3,NF kappa B inhibitor alpha,MAD3,alpha,Major histocompatibility complex enhancer-binding protein MAD3,NF-kappa-B inhibitor alpha,Nuclear factor of kappa light chain gene enhancer in B cells,Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha,nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,pIK KappaBA Alpha
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Phosphorylated human IK KappaBA Alpha (Ser36) peptide
- Klon:
- A819
- Uniprot:
- P25963
- Synonyme:
- EDAID2;I-kappa-B-alpha;IkappaBalpha;ikB-alpha;IKBA;MAD-3;major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;NFKBI;nuclear factor of kappa light chain gene enhancer in B-cells;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
- Weitere Details:
- The NF-K KappaB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IK KappaB proteins. Activation occurs via phosphorylation of IK KappaBA Alpha at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-K KappaB. IK KappaBA Alpha phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IK KappaB at these activating sites have been identified.
- Versandbedingungen:
- Blue Ice