AN302093L
Recombinant Phospho-CD31 (Tyr713) Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302093L
- Zusätzliche Namen:
- PECA,cluster of differentiation,PECAM1,CD31,CD31/EndoCAM,GPIIA,PECA1,PECAM-1,endoCAM,cluster of differentiation 31,Platelet endothelial cell adhesion molecule,endocam,Adhesion molecule,CD31 antigen,CD31 EndoCAM,FLJ34100,FLJ58394,GPIIA',PECAM,Pecam 1,PECAM 1 CD31 EndoCAM,PECAM1,Platelet and endothelial cell adhesion molecule 1,Platelet/endothelial cell adhesion molecule 1,CD31,EndoCAM,GPIIA,PECA1,PECAM-1,Platelet endothelial cell adhesion molecule
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- phosphorylated human CD31 (Tyr713) peptide
- Klon:
- A817
- Uniprot:
- P16284
- Synonyme:
- CD31;CD31 antigen;CD31/EndoCAM;endoCAM;GPIIA';PECA1;PECAM-1;platelet endothelial cell adhesion molecule;platelet endothelial cell adhesion molecule-1
- Weitere Details:
- CD31, also named as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCG Gamma, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.
- Versandbedingungen:
- Blue Ice