Recombinant Phospho-BRD2 (S37) Monoclonal Antibody

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£252.90

War £281.00

SKU:: AN302085L
Zusätzliche Namen:: RNF,BRD,FSRG,RING,KIAA,BRD2-IT,BRD2,BRD2-IT1,D6S113E,FSH,FSRG1,NAT,O27.1.1,RING3,RNF3,KIAA9001
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human BRD2 (phospho S37) fragment
Klon:: A809
Uniprot:: P25440
Synonyme:: BRD2 intronic transcript 1;BRD2-IT1;bromodomain-containing protein 2;D6S113E;female sterile homeotic-related gene 1;FSH;FSRG1;NAT;O27.1.1;really interesting new gene 3 protein;RING3;RNF3
Weitere Details:: Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain. In addition to its involvement in guiding the expression of cell cycle genes through its binding to multiple E2Fs, Brd2 has been shown to be associated with several regulators of transcription, including TFIID and Swi/Snf complexes. First identified as a nuclear serine/threonine kinase, Brd2, like other bromodomain proteins, is thought to function in mammalian development by regulating chromatin structure and transcription. Brd2 has been shown to bind to histone H4 via acetylated Lys12, a substrate of several histone acetyltransferase transcriptional coactivators.