AN302077L
Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN302077L
- Zusätzliche Namen:
- PTPN,PTPN1,PTP1B
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Phosphorylated human PTP1B (Ser352) peptide
- Klon:
- A801
- Uniprot:
- P18031
- Synonyme:
- protein tyrosine phosphatase, placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1
- Weitere Details:
- PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.
- Versandbedingungen:
- Blue Ice