AN302063L
Recombinant PARP2 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302063L
- Zusätzliche Namen:
- ARTD,ADPRT,pADPRT,PARP2,ADPRT2,ADPRTL2,ADPRTL3,ARTD2,PARP-2,pADPRT-2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Klon:
- A783
- Uniprot:
- Q9UGN5
- Synonyme:
- ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2;ADP-ribosyltransferase diphtheria toxin-like 2;ADPRT-2;ADPRT2;ADPRTL2;ADPRTL3;ARTD2;DNA ADP-ribosyltransferase PARP2;hPARP-2;NAD(+) ADP-ribosyltransferase 2;pADPRT-2;PARP-2;poly (ADP-ribose) polymerase family, member 2;poly (ADP-ribosyl) transferase-like 2;poly [ADP-ribose] polymerase 2;poly[ADP-ribose] synthase 2;poly[ADP-ribose] synthetase 2;protein poly-ADP-ribosyltransferase PARP2
- Weitere Details:
- PARP2, also named as ADPRT2 and ADPRTL2, is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADPribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. PARP2 initiates the repair of double-strand DNA breaks: recognizes and binds DNA breaks within chromatin and recruits HPF1, licensing serine ADP-ribosylation of target proteins, such as histones, thereby promoting decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand break.
- Versandbedingungen:
- Blue Ice