AN302050L
Recombinant GOLGA2/GM130 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302050L
- Zusätzliche Namen:
- GOLGA,golgin A,GOLGA2,GM130,golgin A2,130 kDa cis Golgi matrix protein,130 kDa cis-Golgi matrix protein,Cis golgi matrix protein GM130,Gm130 autoantigen,GOGA2,GOLGA 2,Golgi autoantigen,Golgi autoantigen golgin subfamily a 2,Golgi matrix protein GM130,Golgin 95,Golgin subfamily a 2,Golgin subfamily A member 2,Golgin-95,MGC20672,SY11 protein
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Klon:
- A770
- Uniprot:
- Q08379
- Synonyme:
- 130 kDa cis-Golgi matrix protein;GM130;GM130 autoantigen;golgi autoantigen, golgin subfamily a, 2;Golgi matrix protein GM130;golgin subfamily A member 2;golgin-95;SY11 protein
- Weitere Details:
- Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus,and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmicreticulum to the Golgi apparatus and the cell membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at thecis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgidisassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPIvesicles and thereby inhibiting transport through the Golgi apparatus during mitosis. Also plays a key role in spindle pole assembly andcentrosome organization.
- Versandbedingungen:
- Blue Ice