AN302030L
Recombinant CEACAM6 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302030L
- Zusätzliche Namen:
- CEACAM,CEACAM6,CD66c,CEAL,NCA,Carcinoembryonic antigen related cell adhesion molecule 6,Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen),Carcinoembryonic antigen-related cell adhesion molecule 6,CD 66c,CD66c antigen,CEA LIKE PROTEIN,CEACAM 6,CEAM6,MGC93832,Non specific cross reacting antigen,Non-specific crossreacting antigen,Normal cross reacting antigen,Normal cross-reacting antigen
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Klon:
- A750
- Uniprot:
- P40199
- Synonyme:
- carcinoembryonic antigen related cell adhesion molecule 6;carcinoembryonic antigen-related cell adhesion molecule 6;carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen);CD66c;CEAL;Cluster of Differentiation 66c;NCA;Non-specific crossreacting antigen;normal cross-reacting antigen
- Weitere Details:
- Carcinoembryonic antigen (CEA)-related cell adhesion molecule 6 (CEACAM6) is a member of the CEA-related cell adhesion molecule (CEACAM) family. CEACAMs bind to themselves and other family members to carry out numerous cellular functions, including proliferation, signaling, differentiation, tumor suppression, and survival. CEACAM6 is a single-chain, glycosylphosphatidylinositol (GPI)-anchored, highly glycosylated protein that is normally expressed on epithelial cells and granulocytes. CEACAM6 mediates homophilic and heterophilic cell adhesion with other CEA-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils, and plays a role in neutrophil adhesion to cytokine-activated endothelial cells. High levels of CEACAM6 expression are also observed in several different cancers. In cancer, CEACAM6 promotes tumor progression, migration, invasion, and metastasis, and therefore is considered a target for therapeutic intervention.
- Versandbedingungen:
- Blue Ice