AN302028L
Recombinant SPR Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN302028L
- Zusätzliche Namen:
- SDR38C,member,OTTHUMP,SPR,SDR38C1,8 dihydrobiopterin:NADP+ oxidoreductase),member 1,OTTHUMP00000160199,Sepiapterin reductase,Sepiapterin reductase (7,Short chain dehydrogenase/reductase family 38C,SPRE
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Klon:
- A748
- Uniprot:
- P35270
- Synonyme:
- SDR38C1;sepiapterin reductase;sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase);Sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming);short chain dehydrogenase/reductase family 38C, member 1
- Weitere Details:
- SPR can catalyze the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD). In the majority of cases, patients manifest progressive psychomotor retardation, dystonia and spasticity. Cognitive anomalies are also often present. The disease is due to severe dopamine and serotonin deficiencies in the central nervous system caused by a defect in BH4 synthesis.
- Versandbedingungen:
- Blue Ice