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AN302006L

Recombinant CD137 Monoclonal Antibody

Größe

£252.90

War £281.00

SKU:
AN302006L
Zusätzliche Namen:
TNFRSF,Cd137,Ila,Ly63,Tnfrsf9,4-1BB,TNFRSF9
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Mouse
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Peptide. This information is proprietary to PTMab.
Klon:
A726
Uniprot:
P20334
Synonyme:
4-1BB;4-1BB ligand receptor;A930040I11Rik;AA408498;AI325004;Cd137;CD137 antigen;CDw137;ILA;Ly6;Ly63;secreted CD137 antigen;T-cell antigen 4-1BB;tumor necrosis factor receptor superfamily member 9
Weitere Details:
TNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB/CD137/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL/CD137L/TNFSF9 on antigen presenting cells binds to 4-1BB/CD137/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4 1BB/CD137/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4 1BB/CD137/TNFRSF9 by its agonistic antibodies in cancer immunotherapy.
Versandbedingungen:
Blue Ice