AN302005L
Recombinant Tissue Plasminogen Activator Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN302005L
- Zusätzliche Namen:
- PLAT,T-PA,TPA,Tissue plasminogen activator,t-plasminogen activator,Alteplase,DKFZp686I03148,Plasminogen activator tissue,Plasminogen activator tissue type,Reteplase,t PA,T Plasminogen Activator,Tissue plasminogen activator (t PA),Tissue type plasminogen activator,Tissue-type plasminogen activator chain B,TPA1
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Klon:
- A725
- Uniprot:
- P00750
- Synonyme:
- alteplase;plasminogen/activator kringle;reteplase;T-PA;t-plasminogen activator;tissue-type plasminogen activator;TPA
- Weitere Details:
- Plasminogen activator, tissue (PLAT, synonyms: TPA, T-PA) is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein (33 kDa and 32 kDa). PLAT enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA has 4 isoforms produced by alternative splicing with the MW of 63 kDa, 33 kDa, 57 kDa and 44 kDa.
- Versandbedingungen:
- Blue Ice