Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Monoclonal

AN301964L

Recombinant DPP4/CD26 Monoclonal Antibody

Größe

£252.90

War £281.00

SKU:
AN301964L
Zusätzliche Namen:
DPP,dipeptidylpeptidase,dipeptidyl-peptidase,dipeptidyl peptidase,T-cell activation antigen CD,adenosine deaminase complexing protein,DPP4,ADABP,ADCP2,CD26,DPPIV,TP103,Dipeptidyl peptidase IV,ADCP-2,dipeptidyl-peptidase 4,dipeptidyl peptidase 4,DPP IV,dipeptidylpeptidase 4,T-cell activation antigen CD26,adenosine deaminase complexing protein 2,dipeptidylpeptidase IV,Dipeptidyl peptidase IV (DPP IV),ADABP Protein,ADCP2 Protein,CD26 Protein,DPPIV Protein,Human,TP103 Protein
Anwendung:
IHC, WB
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human DPP4/CD26 fragment
Klon:
A680
Uniprot:
P27487
Synonyme:
ADABP;ADCP-2;ADCP2;adenosine deaminase complexing protein 2;CD26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;dipeptidylpeptidase 4;dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2);DPP IV;DPPIV;Gly-Pro naphthylamidase;Post-proline dipeptidyl aminopeptidase IV;T-cell activation antigen CD26;TP103;Xaa-Pro-dipeptidylaminopeptidase
Weitere Details:
DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation.
Versandbedingungen:
Blue Ice