AN301945L
Recombinant Glutamate receptor 3 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301945L
- Zusätzliche Namen:
- MRX,GRIA,GLUR,GluA,GLUR-K,GRIA3,GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94,AMPA 3,AMPA selective glutamate receptor 3,AMPA-selective glutamate receptor 3,dJ1171F9.1,GLUK3,GluR 3,GLUR C,GLUR K3,GluR-3,Glutamate ionotropic receptor AMPA type subunit 3,Glutamate receptor,Glutamate receptor 3,Glutamate receptor C,Glutamate receptor ionotrophic AMPA 3,Glutamate receptor ionotropic,Glutamate receptor subunit 3,GRIA 3,Ionotrophic Glutamate Receptor,ionotropic
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Glutamate receptor 3 fragment
- Klon:
- A661
- Uniprot:
- P42263
- Synonyme:
- AMPA-selective glutamate receptor 3;dJ1171F9.1;GluA3;gluR-3;GLUR-C;GLUR-K3;GLUR3;GLURC;glutamate receptor 3;glutamate receptor C;Glutamate receptor ionotropic, AMPA 3;glutamate receptor subunit 3;glutamate receptor, ionotrophic, AMPA 3;glutamate receptor, ionotropic, AMPA 3;MRX94;MRXSW
- Weitere Details:
- AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Glutamate receptor 3 (GluR3) knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett's syndrome, amyotrophic lateral sclerosis and Alzheimer disease.
- Versandbedingungen:
- Blue Ice