AN301935L
Recombinant beta III Tubulin Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301935L
- Zusätzliche Namen:
- FEOM,beta,CFEOM,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,TUBB4,beta-4,beta Tubulin III,TUBB3,beta 3 tubulin,M(beta)3,M(beta)6,MC1R,Neuron specific beta III Tubulin,Neuron-specific class III beta-tubulin,QccE-11995,QccE-15186,TBB3,Tubb 3,Tubulin beta 3,Tubulin beta 3 chain,Tubulin beta 4,Tubulin beta III,Tubulin beta-3 chain,Tubulin beta-4 chain,Tubulin beta-III
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human beta III Tubulin fragment
- Klon:
- A651
- Uniprot:
- Q13509
- Synonyme:
- beta-4;CDCBM;CDCBM1;CFEOM3;CFEOM3A;class III beta-tubulin;FEOM3;TUBB4;tubulin beta-3 chain;tubulin beta-4 chain;tubulin beta-III;tubulin, beta 3
- Weitere Details:
- Beta III Tubulin (TUBB3) is one of six B Beta-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation). Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS). Microtubules enriched in B Beta3-tubulin are more dynamic than those composed of other B Beta-tubulin isoforms. Research studies have shown that mutations in the B Beta3-tubulin gene TUBB3 cause ocular motility defects and other nervous system disorders. Furthermore, B Beta3-tubulin is present in neoplastic but not in normal differentiated glial cells. Thus, B Beta3-tubulin is a great neuronal marker.
- Versandbedingungen:
- Blue Ice