AN301892L
Recombinant TFF1/pS2 Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN301892L
- Zusätzliche Namen:
- TFF,pNR,HPS,D21S,Protein Ps,Trefoil factor,TFF1,BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2,Breast cancer estrogen-inducible protein,Polypeptide P1.A,Protein Ps2,Trefoil factor 1
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human TFF1/pS2 fragment
- Klon:
- A608
- Uniprot:
- P04155
- Synonyme:
- BCEI;breast cancer estrogen-inducible protein;breast cancer estrogen-inducible sequence;D21S21;gastrointestinal trefoil protein pS2;HP1.A;HPS2;pNR-2;polypeptide P1.A;protein pS2;pS2;trefoil factor 1
- Weitere Details:
- TFF1/pS2 is a gastric peptide that is highly expressed by mucosal goblet cells of the stomach, where it is thought to play a role in maintaining the integrity of the epithelial layer of the mucosa through the regulation of cell-cell adhesion and cell migration. Research studies have shown that TFF1 functions as a tumor suppressor in the stomach as its expression is frequently lost in gastric carcinomas, largely due to promoter hypermethylation. Research studies have also demonstrated that TFF1 is a transcriptional target of estrogen receptor-A Alpha and that TFF1 expression in breast carcinoma may be used as a predictive biomarker for response to anti-estrogen therapy.
- Versandbedingungen:
- Blue Ice