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AN301871L

Recombinant Aconitase 1/ACO1 Monoclonal Antibody

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£252.90

War £281.00

SKU:
AN301871L
Zusätzliche Namen:
HEL,IRP,ACO,IREB,ACO1,ACONS,HEL60,IREB1,IREBP,IREBP1,IRP1,ACO 1,ACOC,Aconitase,Aconitase 1 soluble,Aconitase1,Aconitate hydratase,Citrate hydro lyase,Citrate hydro-lyase,Cytoplasmic aconitate hydratase,Ferritin repressor protein,IRE BP 1,IREB 1,IRE-BP 1,Iron regulatory protein 1,Iron responsive element binding protein 1,Iron-responsive element-binding protein 1,IRP 1,OTTHUMP00000045233
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human Aconitase 1/ACO1 fragment
Klon:
A583
Uniprot:
P21399
Synonyme:
aconitase 1, soluble;aconitate hydratase, cytoplasmic;ACONS;citrate hydro-lyase;cytoplasmic aconitase;cytoplasmic aconitate hydratase;cytosplasmic aconitase;epididymis luminal protein 60;epididymis secretory sperm binding protein;ferritin repressor protein;HEL60;IREB1;IREBP;IREBP1;iron regulatory protein 1;iron-responsive element-binding protein 1;IRP1;soluble aconitase
Weitere Details:
Aconitase 1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA.
Versandbedingungen:
Blue Ice