Recombinant CD1c Monoclonal Antibody

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£252.90

War £281.00

SKU:: AN301843L
Zusätzliche Namen:: CD1C,BDCA-1,R7,T6
Anwendung:: IHC, WB, IP
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human CD1c fragment
Klon:: A555
Uniprot:: P29017
Synonyme:: BDCA1;CD1;CD1A;CD1C antigen, c polypeptide;cortical thymocyte antigen CD1C;differentiation antigen CD1-alpha-3;R7;T-cell surface glycoprotein CD1c
Weitere Details:: CD1c is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1c is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail.