AN301819L
Recombinant RING1B Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN301819L
- Zusätzliche Namen:
- RNF,DinG,Ring1b,Rnf2
- Anwendung:
- Flow Cytometry, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human RING1B fragment
- Klon:
- A531
- Uniprot:
- Q9CQJ4
- Synonyme:
- AI326319;AI450156;AU019207;di;dinG;E3 ubiquitin-protein ligase RING2;Rin;RING finger protein 1B;RING finger protein 2;RING-type E3 ubiquitin transferase RING2;Ring1B
- Weitere Details:
- RING1B is a E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It may be involved in the initiation of both imprinted and random X inactivation. It E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4.
- Versandbedingungen:
- Blue Ice