AN301807L
Recombinant MTAP Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN301807L
- Zusätzliche Namen:
- HEL,MTAP,BDMF,DMSFH,DMSMFH,HEL-249,LGMBF,MSAP,c86fus,5' methylthioadenosine phosphorylase,5''-methylthioadenosine phosphorylase,Epididymis luminal protein 249,HEL 249,MeSAdo phosphorylase,Methylthioadenosine phosphorylase,MTA phosphorylase,MTAPase,S methyl 5 thioadenosine phosphorylase,S methyl 5' thioadenosine phosphorylase,S-methyl-5''-thioadenosine phosphorylase
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human MTAP fragment
- Klon:
- A519
- Uniprot:
- Q13126
- Synonyme:
- 5'-methylthioadenosine phosphorylase;BDMF;c86fus;DMSFH;DMSMFH;epididymis luminal protein 249;epididymis secretory sperm binding protein;HEL-249;LGMBF;MeSAdo phosphorylase;MSAP;MTA phosphorylase;MTAPase;S-methyl-5'-thioadenosine phosphorylase
- Weitere Details:
- MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5'-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. MTAP is expressed in all normal cells and tissues, although frequently lost in different human tumors including pancreatic adenocarcinoma, neuroendocrine tumors, non-small cell lung carcinoma and breast carcinoma, thereby implicating its potential function as a tumor suppressor.
- Versandbedingungen:
- Blue Ice