Recombinant MUC13 Monoclonal Antibody

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£252.90

War £281.00

SKU:: AN301769L
Zusätzliche Namen:: Muc,UNQ,DRCC,DRCC1,RECC,MUC13,UNQ6194,PRO20221,Down-regulated in colon cancer 1
Anwendung:: WB, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human MUC13 fragment
Klon:: A477
Uniprot:: Q9H3R2
Synonyme:: down-regulated in colon cancer 1;DRCC1;MUC-13;mucin 13, epithelial transmembrane;mucin-13
Weitere Details:: Mucin 13 (MUC13) is a high-molecular-weight transmembrane glycoprotein that is frequently and aberrantly expressed in a variety of epithelial carcinomas, including gastric, colorectal, and ovarian cancers. On the basis of the high expression of MUC13 in cancer cells as well as recent laboratory findings suggesting a malignant phenotype of MUC13-transfected cell lines, the oncogenic potential of MUC13 has emerged. The various functional domains of MUC13 may confer oncogenic potential to MUC13. MUC13 exhibits the characteristics suitable as an early marker for cancer screening and presents a promising target for antibody-guided targeted therapy.