AN301762L
Recombinant PI3 Kinase p110 delta Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN301762L
- Zusätzliche Namen:
- IMD,PIK3CD,APDS,IMD14,P110DELTA,PI3K,p110D
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human PI3 Kinase p110 delta fragment
- Klon:
- A470
- Uniprot:
- O00329
- Synonyme:
- APDS;IMD14;IMD14A;IMD14B;p110D;P110DELTA;Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform;phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 20;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8/20;phosphoinositide-3-kinase C;phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta;PI3-kinase p110 subunit delta;PI3K;PI3Kdelta;ptdIns-3-kinase subunit p110-delta;ROCHIS
- Weitere Details:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) belongs to Class I Phosphoinositide-3-kinase (PI3K) which phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides and uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.
- Versandbedingungen:
- Blue Ice