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AN301732L

Recombinant LSD2/AOF1 Monoclonal Antibody

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£252.90

War £281.00

SKU:
AN301732L
Zusätzliche Namen:
AOF,LSD,C6orf,AOF1,C6orf193,LSD2,KDM1B
Anwendung:
Flow Cytometry, WB, IF
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human LSD2/AOF1 fragment
Klon:
A440
Uniprot:
Q8NB78
Synonyme:
AOF1;C6orf193;flavin-containing amine oxidase domain-containing protein 1;LSD2;lysine (K)-specific demethylase 1B;lysine-specific histone demethylase 1B;lysine-specific histone demethylase 2
Weitere Details:
LSD2, also known as AOF1, is a Lysine (K)-specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.
Versandbedingungen:
Blue Ice