AN301675L
Recombinant Thyroglobulin Monoclonal Antibody
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£252.90
War £281.00
- SKU:
- AN301675L
- Zusätzliche Namen:
- TDH,TG,AITD3,TGN,AITD 3,hTG,TDH3,THYG,Thyroglobulin,AITD 3,AITD3,hTG,TDH3,Tg,TGN,THYG,Thyroglobulin
- Anwendung:
- Flow Cytometry, IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Thyroglobulin fragment
- Klon:
- A378
- Uniprot:
- P01266
- Synonyme:
- AITD3;TGN;thyroglobulin
- Weitere Details:
- Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.
- Versandbedingungen:
- Blue Ice