Recombinant QSOX1 Monoclonal Antibody

Größe

£252.90

War £281.00

SKU:: AN301645L
Zusätzliche Namen:: UNQ,PRO,QSOX,QSCN,QSOX1,Q6,QSCN6,UNQ2520,PRO6013,quiescin sulfhydryl oxidase 1
Anwendung:: Flow Cytometry, WB, IP
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human QSOX1 fragment
Klon:: A348
Uniprot:: O00391
Synonyme:: Q6;QSCN6;Quiescin Q6;quiescin Q6 sulfhydryl oxidase 1;sulfhydryl oxidase 1;testis tissue sperm-binding protein Li 62n;thiol oxidase 1
Weitere Details:: QSOX1 belongs to the family of FAD-dependent sulfhydryl oxidases and is an atypical disulfide catalyst. QSOX1 is mainly located in the Golgi apparatus and endoplasmic reticulum (ER) in human embryonic fibroblasts, and it cooperates with protein disulfide isomerase (PDI) to help fold new-born proteins in the cell. QSOX1 is mainly expressed in the heart, placenta, lung, liver, skeletal muscle, and pancreas, and is very weakly expressed in the brain and kidneys. Studies have found that the increase of QSOX1 expression in tumor cells enables tumor cells to actively circumvent the mechanism of apoptosis mediated by reactive oxygen species.