AN301633L
Recombinant PPM1A Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301633L
- Zusätzliche Namen:
- PPM1A,PP2C-ALPHA,PP2CA,PP2Calpha,Protein Phosphatase 1A,Protein Phosphatase 2C Isoform Alpha,Protein Phosphatase IA,PPPM1A
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human PPM1A fragment
- Klon:
- A336
- Uniprot:
- P35813
- Synonyme:
- PP2C-ALPHA;PP2CA;PP2Calpha;protein phosphatase 1A;Protein phosphatase 2C isoform alpha;Protein phosphatase IA
- Weitere Details:
- Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
- Versandbedingungen:
- Blue Ice