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AN301620L

Recombinant PAX8 Monoclonal Antibody

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£252.90

War £281.00

SKU:
AN301620L
Zusätzliche Namen:
Paired box,Paired box gene,Paired domain gene,paired box homeotic gene,PAX,PAX8,OTTHUMP00000158659,OTTHUMP00000158660,OTTHUMP00000203723,OTTHUMP00000203724,Paired box 8,Paired box gene 8,paired box homeotic gene 8,Paired box protein Pax 8,Paired box protein Pax-8,Paired domain gene 8,PAX 8
Anwendung:
IHC, IF
Konzentration:
1 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human PAX8 fragment
Klon:
A323
Uniprot:
Q06710
Synonyme:
paired box protein Pax-8;paired domain gene 8
Weitere Details:
PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid.
Versandbedingungen:
Blue Ice