AN301616L
Recombinant ARPC5/p16 ARC Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301616L
- Zusätzliche Namen:
- ARC,ARPC,dJ127C,ARPC5,ARC16,dJ127C7.3,p16-Arc
- Anwendung:
- Flow Cytometry, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human ARPC5/p16 ARC fragment
- Klon:
- A319
- Uniprot:
- O15511
- Synonyme:
- actin related protein 2/3 complex, subunit 5, 16kDa;actin-related protein 2/3 complex subunit 5;ARC16;arp2/3 complex 16 kDa subunit;Arp2/3 protein complex subunit p16;dJ127C7.3;p16-Arc
- Weitere Details:
- Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
- Versandbedingungen:
- Blue Ice