AN301568L
Recombinant iNOS Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301568L
- Zusätzliche Namen:
- NOS,HEP-NOS,I-NOS,NOS2A,inducible,Inos,MAC-NOS,Inosl,Nitric oxide synthase,NOS type II,Nos2
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human iNOS fragment
- Klon:
- A267
- Uniprot:
- P29477
- Synonyme:
- i-NOS;inducible nitric oxide synthase;inducible NO synthase;inducible NOS;iNOS;MAC-NOS;macrophage NOS;N;nitric oxide synthase 2, inducible, macrophage;nitric oxide synthase, inducible;No;NOS type II;Nos-2;NOS-II;Nos2a;peptidyl-cysteine S-nitrosylase NOS2
- Weitere Details:
- Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.
- Versandbedingungen:
- Blue Ice