AN301514L
Recombinant EphA2 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301514L
- Zusätzliche Namen:
- ARCC,CTPP,EPHA,Ephrin type-A receptor,CTRCT,ARCC2,CTPA,CTPP1,CTRCT6,ECK,EPHA2,Ephrin type-A receptor 2,Epithelial cell kinase,Tyrosine-protein kinase receptor ECK,AW545284,EPH receptor A2,Myk2,Sek2,Sek-2
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human EphA2 fragment
- Klon:
- A213
- Uniprot:
- P29317
- Synonyme:
- ARCC2;CTPA;CTPP1;CTRCT6;ECK;ephrin type-A receptor 2;Epithelial cell kinase;epithelial cell receptor protein tyrosine kinase;soluble EPHA2 variant 1;tyrosine-protein kinase receptor ECK
- Weitere Details:
- Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.
- Versandbedingungen:
- Blue Ice