AN301512L
Recombinant EIF2S1 Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301512L
- Zusätzliche Namen:
- EIF2S,EIF,EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,EIF 2,EIF 2 alpha,EIF 2A,EIF 2alpha,EIF2 alpha,eIF-2-alpha,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit 1 alpha,Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa,Eukaryotic translation initiation factor 2 subunit alpha,IF2A
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human EIF2S1 fragment
- Klon:
- A211
- Uniprot:
- P05198
- Synonyme:
- EIF-2;eIF-2-alpha;EIF-2A;EIF-2alpha;EIF2;EIF2A;eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
- Weitere Details:
- The eukaryotic translation initiation factor 2-A Alpha subunit (EIF2S1) is the first regulatory step that catalyzes the initiation of protein synthesis and promotes the binding of the initial tRNA to the 40S ribosomal subunit. As an important translation initiation factor, the eukaryotic initiation factor 2-A Alpha subunit is regulated by a variety of signal molecules, that is, it functions by regulating the phosphorylation and acetylation status of EIF2S1. Kinases activated by viral infection (PKR), endoplasmic reticulum stress (PERK/PEK), amino acid deprivation (GCN2) or heme deficiency (HRI) can phosphorylate EIF2S1 to regulate the transcription and translation of cell-related genes and enhance Cell protection mechanism.
- Versandbedingungen:
- Blue Ice