Recombinant Complement C4-B Monoclonal Antibody

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£252.90

War £281.00

SKU:: AN301451L
Zusätzliche Namen:: CPAMD,Basic C,Basic C4,C4(Chido Blood Group),C4-B,C4B,C4B_2,CO4,CPAMD3
Anwendung:: IHC, WB
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant human Complement C4-B fragment
Klon:: A146
Uniprot:: P0C0L5
Synonyme:: basic complement C4;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3;C4B_2;C4B1;C4B12;C4B2;C4B3;C4B5;C4BD;C4F;CH;Chido form of C4;CO4;complement C4-B;complement C4-B-like;complement C4B1a;complement component 4B (Chido blood group);CPAMD3
Weitere Details:: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.