AN301450L
Recombinant ABCB11/BSEP Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301450L
- Zusätzliche Namen:
- PGY,ABC,ABCB,BRIC,ABCB11,ABC16,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human ABCB11/BSEP fragment
- Klon:
- A145
- Uniprot:
- O95342
- Synonyme:
- ABC member 16, MDR/TAP subfamily;ABC16;ATP-binding cassette sub-family B member 11;ATP-binding cassette, sub-family B (MDR/TAP), member 11;bile salt export pump;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;progressive familial intrahepatic cholestasis 2;sister p-glycoprotein;SPGP
- Weitere Details:
- Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates to hepatic bile acids homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts. Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion.
- Versandbedingungen:
- Blue Ice