AN301414L
Recombinant Histone H2A (Acetyl Lys5) Monoclonal Antibody
Größe
£252.90
War £281.00
- SKU:
- AN301414L
- Zusätzliche Namen:
- H2AFM,HIST1H2AB,H2AFA,HIST1H2AE,H2AC4,H2AC8
- Anwendung:
- ChIP, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Acetylated human histone H2A (Lys5) peptide
- Klon:
- A109
- Uniprot:
- P04908
- Synonyme:
- H2A histone family, member A;H2A histone family, member M;H2A.1;H2A.2;H2A/a;H2A/m;H2AC4;H2AC8;H2AFA;H2AFM;HIST1H2AB;HIST1H2AE;histone 1, H2ab;histone 1, H2ae;histone cluster 1 H2A family member b;histone cluster 1 H2A family member e;histone cluster 1, H2ab;histone cluster 1, H2ae;histone H2A type 1-B/E;Histone H2A.2;histone H2A/a;histone H2A/m;histone H2AE
- Weitere Details:
- Histone post-translational modifications (PTMs), known as the "histone code", are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc.
- Versandbedingungen:
- Blue Ice