AN301388L
Recombinant Phospho-PERK (Thr980) Monoclonal Antibody
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£311.40
War £346.00
- SKU:
- AN301388L
- Zusätzliche Namen:
- EIF2AK,Pek,Perk,Eif2ak3
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- A synthetic peptide corresponding to residues around (Thr980) of Mouse Phospho-PERK
- Klon:
- B1155
- Uniprot:
- Q9Z2B5
- Synonyme:
- eukaryotic translation initiation factor 2-alpha kinase 3;pancreatic eIF2-alpha kinase;PE;Pek;Perk;PRKR-like endoplasmic reticulum kinase
- Weitere Details:
- The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
- Versandbedingungen:
- Blue Ice