AN301368L
Recombinant E2F-1 Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN301368L
- Zusätzliche Namen:
- RBP,RBAP,RBBP,E2F,E2F-1,RBAP1,RBBP3,RBP3,E2F1
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human E2F-1 protein
- Klon:
- B1135
- Uniprot:
- Q01094
- Synonyme:
- E2F-1;PBR3;PRB-binding protein E2F-1;RBAP-1;RBAP1;RBBP-3;RBBP3;RBP3;retinoblastoma-associated protein 1;retinoblastoma-binding protein 3;transcription factor E2F1
- Weitere Details:
- The protein encoded by this gene is a member ofThe E2F family of transcription factors.The E2F family plays a crucial role inThe control of cell cycle and action of tumor suppressor proteins and is also a target ofThe transforming proteins of small DNA tumor viruses.The E2F proteins contain several evolutionally conserved domains found in most members ofThe family. These domains include a DNA binding domain, a dimerization domain which determines interaction withThe differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded withinThe transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner.
- Versandbedingungen:
- Blue Ice