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AN301307L

Recombinant Phospho-4E-BP1 (Thr37/46)) Monoclonal Antibody

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£311.40

War £346.00

SKU:
AN301307L
Zusätzliche Namen:
4EBP,eIF4E binding protein,eukaryotic translation initiation factor 4E-binding protein,4E-BP,EIF4EBP,EIF4EBP1,4E-BP1,4EBP1,BP-1,PHAS-I,eukaryotic translation initiation factor 4E-binding protein 1,BP 1,eIF4E binding protein 1,eIF4E-binding protein 1,PHASI,Phosphorylated heat- and acid-stable protein regulated by insulin 1,4EBP1,4E-BP1,BP-1,eukaryotic translation initiation factor 4E-binding protein 1,PHAS-I,4E BP1
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
A synthetic peptide corresponding to residues around (Thr37/46) of Human Phospho-4E-BP1
Klon:
B1070
Uniprot:
Q13541
Synonyme:
4E-BP1;4EBP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1
Weitere Details:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5&apos, end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Versandbedingungen:
Blue Ice