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AN301257L

Recombinant Raf-B Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:
AN301257L
Zusätzliche Namen:
RAFB,BRAF,B-RAF1,B-raf,BRAF1,NS7,RAFB1,serine/threonine-protein kinase B-raf,B-raf,BRAF1,B-RAF1,NS7,RAFB1,serine/threonine-protein kinase B-raf,94 kDa B raf protein,B raf 1,B Raf proto oncogene,B Raf proto oncogene serine threonine protein kinase,B RAF1,BRAF 1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),cRmil,FLJ95109,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,Oncogen BRAF,oncogene BRAF1,p94,proto-oncogene
Anwendung:
IHC
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human Raf-B protein
Klon:
B1020
Uniprot:
P15056
Synonyme:
94 kDa B-raf protein;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);B-Raf serine/threonine-protein;B-RAF1;BRAF1;murine sarcoma viral (v-raf) oncogene homolog B1;NS7;p94;proto-oncogene B-Raf;RAFB1;serine/threonine-protein kinase B-raf;v-raf murine sarcoma viral oncogene homolog B;v-raf murine sarcoma viral oncogene homolog B1
Weitere Details:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Versandbedingungen:
Blue Ice