Recombinant PDE1B Monoclonal Antibody

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£221.40

War £246.00

SKU:: AN301230L
Zusätzliche Namen:: PDE1B,HEL-S-79p,PDE1B1,PDES1B
Anwendung:: WB
Konzentration:: 0.2 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human PDE1B protein
Klon:: B989
Uniprot:: Q01064
Synonyme:: 63 kDa Cam-PDE;calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B;calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase;calmodulin-stimulated phosphodiesterase PDE1B1;cam-PDE 1B;epididymis secretory sperm binding protein Li 79p;HEL-S-79p;PDE1B1;PDES1B;phosphodiesterase 1B, calmodulin-dependent;presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Weitere Details:: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.