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AN301225L

Recombinant BRAT1 Monoclonal Antibody

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£221.40

War £246.00

SKU:
AN301225L
Zusätzliche Namen:
BRAT,BAAT,C7orf,BRAT1,BAAT1,C7orf27,RMFSL
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human BRAT1 protein
Klon:
B984
Uniprot:
Q6PJG6
Synonyme:
BAAT1;BRCA1-associated ATM activator 1;BRCA1-associated protein required for ATM activation protein 1;C7orf27;HEAT repeat-containing protein C7orf27;NEDCAS;RMFSL
Weitere Details:
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.
Versandbedingungen:
Blue Ice