Recombinant OXGR1 Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:: AN301217L
Zusätzliche Namen:: P2Y,OXGR,P2RY,GPR,OXGR1,GPR80,GPR99,P2RY15,P2Y15,aKGR
Anwendung:: WB
Konzentration:: 0.2 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human OXGR1 protein
Klon:: B976
Uniprot:: Q96P68
Synonyme:: 2-oxoglutarate receptor 1;aKGR;alpha-ketoglutarate receptor 1;G protein-coupled receptor 80;G-protein coupled receptor 80;G-protein coupled receptor 99;GPR80;GPR99;oxoglutarate (alpha-ketoglutarate) receptor 1;P2RY15;P2Y purinoceptor 15;P2Y-like GPCR;P2Y-like nucleotide receptor;P2Y15;seven transmembrane helix receptor
Weitere Details:: This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants.