AN301163L
Recombinant GPX1 Monoclonal Antibody
Größe
£221.40
War £246.00
- SKU:
- AN301163L
- Zusätzliche Namen:
- GPX,Gpx-,Glutathione peroxidase,GPXD,GSHPX1,GPX1,GPx-1,GSHPx-1,Glutathione peroxidase 1,Cellular glutathione peroxidase,GPX1
- Anwendung:
- IHC, WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human GPX1 protein
- Klon:
- B922
- Uniprot:
- P07203
- Synonyme:
- cellular glutathione peroxidase;glutathione peroxidase 1;GPXD;GSHPx-1;GSHPX1;selenoprotein GPX1
- Weitere Details:
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site.
- Versandbedingungen:
- Blue Ice