AN301105L
Recombinant NOX2 Monoclonal Antibody
Größe
£221.40
War £246.00
- SKU:
- AN301105L
- Zusätzliche Namen:
- IMD,NOX,GP91,AMCBX,AMCBX2,CGD,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX,CYBB,beta polypeptide,CGD91-phox,CY24B,Cytochrome b 245,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,p22 phagocyte B-cytochrome,P91 PHOX,Superoxide-generating NADPH oxidase heavy chain subunit,gp91-phox
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human NOX2 protein
- Klon:
- B860
- Uniprot:
- P04839
- Synonyme:
- AMCBX2;CGD;CGD91-phox;CGDX;cytochrome b-245 beta polypeptide;cytochrome b-245 heavy chain;cytochrome b(558) subunit beta;cytochrome b558 subunit beta;GP91-1;GP91-PHOX;GP91PHOX;heme-binding membrane glycoprotein gp91phox;IMD34;NADPH oxidase 2;neutrophil cytochrome b 91 kDa polypeptide;NOX2;p22 phagocyte B-cytochrome;p91-PHOX;superoxide-generating NADPH oxidase heavy chain subunit
- Weitere Details:
- Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell&apos,s respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
- Versandbedingungen:
- Blue Ice