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AN301081L

Recombinant MiTF Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:
AN301081L
Zusätzliche Namen:
CMM,bHLHe,MITF,CMM8,COMMAD,MI,WS2,WS2A,bHLHe32
Anwendung:
IHC, WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human MiTF protein
Klon:
B836
Uniprot:
O75030
Synonyme:
bHLHe32;class E basic helix-loop-helix protein 32;CMM8;COMMAD;melanogenesis associated transcription factor;MI;microphtalmia-associated transcription factor;microphthalmia-associated transcription factor;MITF-A;WS2;WS2A
Weitere Details:
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Versandbedingungen:
Blue Ice