AN301013L
Recombinant Smad2 Monoclonal Antibody
Größe
£221.40
War £246.00
- SKU:
- AN301013L
- Zusätzliche Namen:
- MADH,MADR,hMAD,SMAD,hSMAD,JV18,JV18-1,MADH2,MADR2,hMAD-2,hSMAD2,Smad2,Drosophila,homolog of,hSMAD family member 2,JV181,MAD,MAD homolog 2,MAD Related Protein 2,Mad-related protein 2,MGC22139,MGC34440,Mother against DPP homolog 2,Mothers against decapentaplegic,Mothers against decapentaplegic homolog 2,Mothers against DPP homolog 2,OTTHUMP00000163489,Sma and Mad related protein 2,Sma- and Mad-related protein 2 MAD,SMAD 2,SMAD family member 2
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Smad2 protein
- Klon:
- B764
- Uniprot:
- Q15796
- Synonyme:
- hMAD-2;hSMAD2;JV18;JV18-1;MAD homolog 2;Mad-related protein 2;MADH2;MADR2;mother against DPP homolog 2;mothers against decapentaplegic homolog 2;Sma- and Mad-related protein 2;SMAD family member 2;SMAD, mothers against DPP homolog 2
- Weitere Details:
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene &apos,mothers against decapentaplegic&apos, (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation.
- Versandbedingungen:
- Blue Ice