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AN300969L

Recombinant NRAS Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:
AN300969L
Zusätzliche Namen:
ALPS,HRAS,NRAS,ALPS4,CMNS,N-ras,NCMS,NRAS1,NS6,GTPase NRas,GTPase,HRAS1,RASN,Transforming protein N-Ras,AV095280,N ras,N ras protein part 4,Neuroblastoma RAS viral (v ras) oncogene homolog,OTTHUMP00000013879,OTTMUSP00000023521,Transforming protein N Ras,v ras neuroblastoma RAS viral oncogene homolog,N-RAS
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human NRAS protein
Klon:
B720
Uniprot:
P01111
Synonyme:
ALPS4;CMNS;GTPase NRas;N-ras;N-ras protein part 4;NCMS;neuroblastoma RAS viral (v-ras) oncogene homolog;neuroblastoma RAS viral oncogene homolog;NRAS1;NS6;transforming protein N-Ras;v-ras neuroblastoma RAS viral oncogene homolog
Weitere Details:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Versandbedingungen:
Blue Ice