AN300963L
Recombinant TDP43 Monoclonal Antibody
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£221.40
War £246.00
- SKU:
- AN300963L
- Zusätzliche Namen:
- ALS,TDP,ALS10,TDP-43,TARDBP,TDP43,along with a truncated 20-28 kDa form,and 99% aa identity with rat TDP-43.,human and mouse TDP-43 share 100% aa sequence identity,in ubiquitin-containing inclusion bodies. TDP-43 can also influence CFTR exon 9 skipping in cystic fibrosis. Within aa 1-103,TDP-43 (TAR DNA binding protein of 43 kDa,TADBP
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human TDP43 protein
- Klon:
- B714
- Uniprot:
- Q13148
- Synonyme:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43
- Weitere Details:
- TAR DNA binding protein(TARDBP) Homo sapiens HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
- Versandbedingungen:
- Blue Ice