AN300801L
Recombinant Prostate Specific Membrane Antigen (PSMA) Monoclonal Antibody
Größe
£221.40
War £246.00
- SKU:
- AN300801L
- Zusätzliche Namen:
- GCP,GIG,Folate hydrolase,Glutamate carboxypeptidase,NAALAD,FGCP,FOLH,GCP2,GCPII,NAALAD1,NAALAdase,PSM,PSMA,mGCP,FOLH1,Cell growth-inhibiting gene 27 protein,Folate hydrolase 1,Glutamate carboxypeptidase 2,NAALADase I,N-acetylated alpha-linked acidic dipeptidase 1|cell growth-inhibiting protein 27|folate hydrolase 1|folylpoly-gamma-glutamate carboxypep,GIG27,FGCP,FOLH,GCP2,GCPII,NAALAD1,NAALAdase,PSM,PSMA,mGCP,FOLH1,Prostate-Specific Membrane Antigen (PSMA)
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Prostate Specific Membrane Antigen (PSMA) protein
- Klon:
- B744
- Uniprot:
- Q04609
- Synonyme:
- cell growth-inhibiting gene 27 protein;FGCP;Folate hydrolase 1;FOLH;folylpoly-gamma-glutamate carboxypeptidase;GCP2;GCPII;glutamate carboxylase II;glutamate carboxypeptidase 2;glutamate carboxypeptidase II;membrane glutamate carboxypeptidase;mGCP;N-acetylated alpha-linked acidic dipeptidase 1;N-acetylated-alpha-linked acidic dipeptidase I;NAALAD1;NAALADase I;prostate specific membrane antigen variant F;Prostate-specific membrane antigen;PSM;PSMA;pteroylpoly-gamma-glutamate carboxypeptidase
- Weitere Details:
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.
- Versandbedingungen:
- Blue Ice