AN300790L
Recombinant Chk1 Monoclonal Antibody
Größe
£221.40
War £246.00
- SKU:
- AN300790L
- Zusätzliche Namen:
- CHK,CHEK,CHEK1,CHK1
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human Chk1 protein
- Klon:
- B733
- Uniprot:
- O14757
- Synonyme:
- cell cycle checkpoint kinase;Checkpoint kinase-1;Checkpoint, S. pombe, homolog of, 1;CHK1;CHK1 checkpoint homolog;Chk1-S;serine/threonine-protein kinase Chk1
- Weitere Details:
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
- Versandbedingungen:
- Blue Ice