Recombinant SRP72 Monoclonal Antibody

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£221.40

War £246.00

SKU:: AN300783L
Zusätzliche Namen:: HEL,SRP,BMFS,SRP72,BMFF,BMFS1,HEL103
Anwendung:: WB
Konzentration:: 0.2 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human SRP72 protein
Klon:: B726
Uniprot:: O76094
Synonyme:: BMFF;BMFS1;epididymis luminal protein 103;HEL103;signal recognition particle 72 kDa protein;signal recognition particle 72kD;signal recognition particle 72kDa;signal recognition particle subunit SRP72
Weitere Details:: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.