Recombinant NABC1 Monoclonal Antibody

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£221.40

War £246.00

SKU:: AN300741L
Zusätzliche Namen:: AIBC,NABC,BCAS,AIBC1,NABC1,BCAS1,BCAS1
Anwendung:: WB
Konzentration:: 0.2 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human NABC1 protein
Klon:: B680
Uniprot:: O75363
Synonyme:: AIBC1;amplified and overexpressed in breast cancer;breast carcinoma amplified sequence 1;breast carcinoma-amplified sequence 1;NABC1;novel amplified in breast cancer 1;PMES-2;protein having mRNA enriched in synaptosomes 2
Weitere Details:: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene.